Mozilla Thunderbird
Free and open-source 1 email client that also functions as a personal information manager with a calendar and contactbook, as well as an RSS feed reader, chat client (IRC/XMPP/Matrix), and news client.
— Mozilla Thunderbird - Wikipedia
Since thunderbird support all organizing and email related features, I use it as all-in-one email client, plus it’s open-source and now have mobile clients.
Actual shortcuts and main features aviable in thunderbird documentation 2.